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However, very little research has been done on this topic

Heres a detailed overview of key ones, including their targets and status

GM2 gangliosidosis includes several genetically distinct disorders, the best known of which are Tay-Sachs disease and Sandhoff disease

the therapy of the disease is now well standardised from the point of view of the timing of therapy: the first approach in order of time is pharmacological, and then later, whenever the progression of the disease has been arrested and medical therapy has proved insufficient to remedy the deformity of the penis or the erectile deficit induced by La Peyronie's disease, surgical therapy is resorted to