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Amyloid beta (1IYT) with a binding energy of 46.1 kcal/mol showed interactions with essential amino acids, viz., ASN27, GLY29, GLY25, LYS28, SER26

Despite these advances, most available studies rely on in vitro models, small patient cohorts, or lack robust clinical validation, limiting the generalizability of current findings

Koinuma D, Tsutsumi S, Kamimura N, Taniguchi H, Miyazawa K, Sunamura M, Imamura T, Miyazono K, Aburatani H: Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling

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