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Emanuele et al., 2021

INTRINSIC AND ADAPTIVE RESISTANCE: THE TUMOR'S MULTI-LAYERED DEFENSE NETWORK Even in scenarios where ATO uptake and some degree of metabolic activation occur, tumor cells often deploy a formidable array of defensive countermeasures that confer intrinsic or adaptive resistance

In contrast, the Oxidized market focuses on traditional, often less sustainable practices that provide immediate gratification and lower initial costs

32,36 Therefore, on the basis of the in vivo self-assembly nanotechnology developed by our group, we designed a PSMA-targeted nano-PROTAC (Psa-AR) with a proximity degradation effect