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10.1111/j.1439-0507.2011.02158.x 209 MllerJ.WeilerM.SchneeweissA.HaagG

ERK5 is a known weak client of Hsp90, and prolonged occupancy of the N-terminal ATP-binding pocket by potent inhibitors such as ganetespib or by HLX itself destabilizes a subset of Hsp90 clients, including ERK5 [48,49,50]

Blackman MR, Sorkin JD, Munzer T, Bellantoni MF, Busby-Whitehead J, Stevens TE, Jayme J, OConnor KG, Christmas C, Tobin JD, Stewart JK, Cottrell E, St Clair C, Pabst KM, Harman SM