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In addition, Coenzyme Q10 supports cellular repair mechanisms, aiding in the regeneration and maintenance of healthy tissues

A 2023 Cochrane review found that Cerebrolysin provided no clear benefit for preventing death in acute ischemic stroke, and noted a potentially higher rate of spontaneous adverse events in some trial subgroups

Santos-Neto et al., 2019), in the African meningitis belt, it is between 10 and 20% but reaches 80% during outbreaks (Tefera et al., 2020), while in Asian countries it is generally low (1.5-9.1%) (Serra et al., 2020)

Additionally, metabolic dysregulation of metal ions such as iron, copper, and manganese in the brain can catalyze Fenton reactions, generating reactive oxygen species that exacerbate OS and protein misfolding [31]