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Mechanistically, these agents share overlapping and complementary actions that could synergistically target the redox-endocrine disturbances characteristic of PCOS

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At the same time, in our previous study on the protective effect of Ebselen on renal ischemia-reperfusion injury, we found that the expression level of GPX3 in renal tissues decreased after renal IRI, and when the level of GPX3 increased after the use of Ebselen, the pathological damage of renal histologic damage was alleviated, and we speculated that GPX3 may play an important role in the oxidative stress response of renal ischemia-reperfusion injury (Wu et al., 2022)

Therefore, each type of vaccine should be injected at least 1 month between the shots