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A Functionally Defined In Vivo Astrocyte Population Identified by C-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (IeAstrocytes) eNeuro

It may present at any age, although its peak incidence is during the childbearing years, between 15 and 45, at which time the female-to-male ratio climbs, reaching a peak ratio of approximately 12 :1