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Glutathione is involved in the regulation of cellular proliferation, apoptosis (programmed cell death), and signal transduction pathways within the brain

Although there are limited published data on its potential benefits as a mucolytic agent in bronchiectasis (CF and non-CF bronchiectasis), our experience suggests it is being used in clinical practice in lung diseases associated with tenacious and copious sputum production, such as in allergic bronchopulmonary aspergillosis and bronchiectasis regardless of cause, and there is anecdotal evidence for the use of oral NAC as an antioxidant for IPF

Patient cells are transduced with a viral vector in a laboratory setting (typically retrovirus or lentivirus) with the result being a set of gene-modified cells carrying copies of the functional gene that can be readministered to the patient

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