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Research led by New York University Grossman School of Medicine and the Institute of Medical Biochemistry Leopoldo de Meis in Brazil has identified two biomarkers in the blood that decrease as cognitive decline and Alzheimers disease progresses

Change history 16 April 2015 This article has been corrected since Online Publication and a corrigendum has also been published Abbreviations ACNU: nimustine BSO: buthionine sulfoximine CNU: chloroethylating nitrosourea CTR1: copper transport channel DSBs: double-strand breaks GSH: glutathione GST: glutathione S -transferase HCR: host-cell reactivation ICL: interstrand crosslink MGMT: O 6 -methylguanine-DNA methyltransferase NAC: N -acetyl cysteine NER: nucleotide excision repair (O 6 MeG): O 6 -methylguanine TMZ: temozolomide References Wen PY, Kesari S

Participants taking Extramel experienced 22% reduction in perceived stress within 4 weeks compared to placebo groups

It also limited neutrophil infiltration, lung edema, and significantly ameliorated histological changes (924, 925)