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Chapter 6, section 20.5.2 of the IMO's LCD Reference Manual was updated to section 20.5.3

10.1021/tx7001405 16 DuF.LiuT.LiuT.WangY.WanY.XingJ

Preclinical research has linked BPC-157 to upregulation of VEGFR2 (vascular endothelial growth factor receptor 2), a mechanism associated with new blood vessel formation, or angiogenesis, in animal injury models

Further mechanistic investigations demonstrate that nicotine inhibits peripheral nerve regeneration and pain through regulating PTEN and downstream anti-inflammatory pathways in an 7-nAChR-dependent manner