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Description

Source: Cruzat, V

FIGURE 8 FIGURE 9 4 Discussion 4.1 Successful establishment of the rat model The successful establishment of a MA poisoning model in this study was confirmed by the markedly elevated concentrations of methanol and formic acid detected in the plasma and ocular tissues of the rats, demonstrating the absorption, metabolic conversion, and subsequent accumulation of the MA in target organs

67 Moreover, KAT2B has also been identified to directly catalyze early growth response 1 (EGR1) lactylation at lysine 364, serving as a writer of lactylation