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10.1016/j.enzmictec.2020.109727 87 SantosA

This is based on the current body of research and our observations of trends in the scientific community

This suggests that nucleic acids do not accumulate in nature but are biodegraded to the simplest monomers and are then used to construct new sequences of DNA and RNA within living organisms

3.2.2 TGF--induced mitochondrial ROS production Mitochondria are the primary intracellular source of ROS, and TGF-1 markedly enhances their production across multiple cell types, contributing to apoptosis, senescence, epithelialmesenchymal transition (EMT), and fibrotic gene expression associated with myofibroblast differentiation [58]