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Clin Pharmacol 14 (2022): 6167

Although evidence supports peripheral-central correlation, future studies with cerebrospinal fluid analysis would provide more direct evidence of brain OS changes during ECT

The entry of -KG into the TCA cycle is highly regulated: Pyruvate Dehydrogenase Complex (PDC): The conversion of pyruvate to acetyl-CoA is tightly regulated by the PDC complex, which can be inhibited by acetyl-CoA (feedback inhibition) and activated by ADP