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Targeting the insulin receptor: nanoparticles for drug delivery across the blood-brain barrier (BBB)

Zheng M, Zhang W, Chen X, Guo H, Wu H, Xu Y, et al

In these patients, benefits have variably included reduced fat mass, increased lean mass, increased bone density, improved lipid profile, reduced cardiovascular risk factors, and improved psychosocial well-being

By donating electrons or hydrogen atoms, curcumin can terminate free radical chain reactions, thus protecting cellular lipids, proteins, and DNA from oxidative damage ( Across oral and periodontal models, curcumin activates cytoprotective antioxidant pathways (e.g., Nrf2/HO-1) and restores redox balance, limiting downstream tissue injury