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Description

Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators

Panganiban J, Kehar M, Ibrahim SH, Hartmann P, Sood S, Hassan S, Ramirez CM, Kohli R, Censani M, Mauney E, Cuda S

Unlike HGH 176-191, AOD9604 contains a modification at the tyrosine (Tyr) position , designed to improve stability and potential interaction with cellular receptors

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