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Results DMF activates the TSS pathway in SCD erythroblasts To investigate the mechanism of DMF on ferroptosis regulation, we conducted untargeted LC-MS using erythroblasts generated from CD34+ stem cells isolated from the peripheral blood of SCD patient

Neurologic symptoms of pellagra include headache, fatigue, apathy, depression, ataxia, poor concentration, delusions, and hallucinations, which can lead to confusion, memory loss, psychosis, and eventual death (27)